2-Bromo-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine - Names and Identifiers
Name | 2-Bromopyridine-4-boronic acid pinacol ester
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Synonyms | 2-Bromo-4-pyridylboronic Acid Pinacol Ester 2-Bromopyridine-4-boronic acid pinacol ester 2-BROMOPYRIDINE-4-BORONIC ACID PINACOL ESTER 2-broMo-4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine 2-(2-Bromo-4-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-bromo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 2-BROMO-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE 2-Bromo-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine Pyridine, 2-bromo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
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CAS | 458532-82-6
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InChI | InChI=1/C11H15BBrNO2/c1-10(2)11(3,4)16-12(15-10)8-5-6-14-9(13)7-8/h5-7H,1-4H3 |
2-Bromo-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine - Physico-chemical Properties
Molecular Formula | C11H15BBrNO2
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Molar Mass | 283.96 |
Density | 1.34±0.1 g/cm3(Predicted) |
Melting Point | 80-83°C |
Boling Point | 354.7±27.0 °C(Predicted) |
Flash Point | 168.3°C |
Water Solubility | Insoluble in water. |
Vapor Presure | 6.71E-05mmHg at 25°C |
pKa | -0.05±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.527 |
MDL | MFCD06798252 |
2-Bromo-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine - Introduction
2-Bromopyridine-4-boronic acid pinacol ester is an organic compound whose chemical formula is C11H15BBrNO2. The following is an introduction to its nature, use, formulation and safety information:
Nature:
-Appearance: 2-Bromopyridine-4-boronic acid pinacol ester is a colorless or pale yellow solid.
-Melting point: about 80-90°C.
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and acetonitrile.
Use:
- 2-Bromopyridine-4-boronic acid pinacol ester is commonly used in the field of organic synthesis as a reagent for chemical reactions. It is an effective substitution reagent and can participate in a variety of important organic conversion reactions, such as Suzuki reaction.
-It can also be used in drug research and synthesis, as well as the synthesis of heterocyclic compounds.
Preparation Method:
- 2-Bromopyridine-4-boronic acid pinacol ester can be prepared by a variety of synthetic methods, the most commonly used of which is the reaction of 2-bromopyridine and 4-boronic acid pinacol. The reaction is usually carried out under an inert atmosphere, and the reaction is carried out by heating the solution.
Safety Information:
- 2-Bromopyridine-4-boronic acid pinacol ester is relatively safe for the human body under normal operating conditions. However, any chemical substances should be handled correctly, personal protective equipment should be worn, and laboratory safety measures should be followed, such as the use of appropriate ventilation systems and protective gloves, glasses, etc.
-Although no significant toxicity or danger reports have been found for 2-Bromopyridine-4-boronic acid pinacol ester, care should be taken when using it and all relevant safety guidelines and laboratory specifications should be followed.
Last Update:2024-04-09 20:45:29